Gene amplification and analysis, volume 1

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چکیده

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The Relationship Between Fibroblastic Growth Factor Receptor-1 (FGFR1) Gene Amplification in Triple Negative Breast Carcinomas and Clinicopathological Prognostic Factors

Background & Objective: In Triple-Negative Breast Cancers (TNBCs), estrogen receptor (ER), progesterone receptor (PR) and HER2/neu genes are not expressed. Fibroblastic Growth Factor Receptor-1 (FGFR1) gene product is a protein that acts as a receptor of thyrosin kinase. It plays a role in the proliferation, differentiation, and migration of malignant cells. The objective was t...

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Analysis of HER2 gene amplification using Differential PCR in breast cancer patients of Isfahan Province

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ژورنال

عنوان ژورنال: FEBS Letters

سال: 1982

ISSN: 0014-5793

DOI: 10.1016/0014-5793(82)80551-6